# Information on the graphical user interface

In order to run our first Eye2Brain application, we have to create a new instance that, in our case, corresponds to one patient.

Figure 1. Experiments web page of the MSO4SC Portal

Firstly, the user has to click on "Experiments" then "Instances" and finally "Add a new one" in order to reach the web page depicted in Fig. 1. Then the application has to be selected and, in particular for the Eye2Brain applications, the user has the possiblity to choose between:

• Level 0: `eye2brain-level-0`

• Level 1: `eye2brain-level-1`

• Level 2: `eye2brain-level-2`

These applications are relevant in the clinical research and medical context. We provide however an advanced interface for developers and end-users who require a fine tuning of some advanced input parameters. The parameters marked advanced below are available only in the advanced interfaces associated with each level in the following applications

• `eye2brain-level-0-advanced`

• `eye2brain-level-1-advanced`

• `eye2brain-level-2-advanced`

At this point all the inputs of the three different models are already filled with some default values in order to have always all the parameters specified. We present now the various input parameters that are available for the three different levels.

## 1. Level 0 - input parameters

 Key name Brief description Default value Unit DBP Diastolic Blood Pressure 69 $mmHg$ SBP Systolic Blood Pressure 116 $mmHg$ HR Heart Rate 69 $bpm$ IOP IntraOcular Pressure 17 $mmHg$ RLTp RetroLaminar Tissue Pressure 9.5 $mmHg$
Level 0 input minimal interface

## 2. Level 1 - input parameters

 Key name Brief description Default value Unit Advanced Interface DBP Diastolic Blood Pressure 69 $mmHg$ SBP Systolic Blood Pressure 116 $mmHg$ HR Heart Rate 69 $bpm$ IOP IntraOcular Pressure 17 $mmHg$ RLTp RetroLaminar Tissue Pressure 9.5 $mmHg$ CRVp Central Retinal Vein Pressure 19 $mmHg$ $\kappa$ permeability coefficient 0.015192 $cm^3\: s\: Kg^{-1}$ [✔]
Level 1 input minimal interface

## 3. Level 2 - input parameters

 Key name Brief description Default value Unit Advanced Interface DBP Diastolic Blood Pressure 69 $mmHg$ SBP Systolic Blood Pressure 116 $mmHg$ HR Heart Rate 69 $bpm$ IOP IntraOcular Pressure 17 $mmHg$ RLTp RetroLaminar Tissue Pressure 9.5 $mmHg$ CRVp Central Retinal Vein Pressure 19 $mmHg$ CRAp Central Retinal Artery Pressure 80 $mmHg$ $\kappa$ permeability coefficient 0.015192 $cm^3\: s\: Kg^{-1}$ [✔] $\rho$ tissue density 0.0011 $Kg\:cm^{-3}$ [✔] $\lambda$ Lamé first parameter 5.88 $GPa$ [✔] $\mu$ Lamé second parameter 0.12 $GPa$ [✔]
Level 2 input minimal interface

 Key name Brief description Default value `feelpp_e2b_cli` extra command line options `job_max_time` maximum allowed time for run (minutes and seconds) 00:30:00 `job_partition` partition to be used on the supercomputer thinnodes `job_tasks` number of tasks to be used in parallel 10 `HPC: primary` code name of the HPC machine to be used (set up in settings) FT2